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2008 · 210 episodes
Episode 1 · 60 min
Julie Bowen / Jonathan Winters / Priscilla Ahn
Episode 2 · 60 min
Katey Sagal / Nathan Fillion
Episode 3 · 60 min
Julie Chen / Maria Bello / Shelby Lynne
Episode 4 · 60 min
Eva Longoria / Neal McDonough
Episode 5 · 60 min
Kal Penn / Gabe Dixon Band
Episode 6 · 60 min
Julie Chen / Neil Patrick Harris / Sophia Myles
Episode 7 · 60 min
Russell Brand / Margaret Cho
Episode 8 · 60 min
Alice Cooper / AnnaLynne McCord
Episode 9 · 60 min
Lynn Ferguson / Lance Morrow
Episode 10 · 60 min
Seann William Scott / Lena Heady
Episode 11 · 60 min
Julie Chen / Jason Biggs / The Ting Tings
Episode 12 · 60 min
Paulina Porizkova / Ken Tucker / Tally Hall
Episode 13 · 60 min
Alan Alda / Illeana Douglas
Episode 14 · 60 min
Jason Segel / Dr Dog / Steve Hofstetter
Episode 15 · 60 min
Kristen Bell / Josh Radnor
Episode 16 · 60 min
Denis Leary / Marianne Jean-Baptiste
Episode 17 · 60 min
John Krasinski / Lisa Masterson
Episode 18 · 60 min
Michael Clarke Duncan / Shirley Manson / Jamie Lidell
Episode 19 · 60 min
Tim Gunn / Elizabeth Reaser
Episode 20 · 60 min
Drew Carey / Tony Parker / Lady Antebellum
Episode 21 · 60 min
Melina Kanakaredes / Gina Carano / Amy Macdonald
Episode 22 · 60 min
Tim Daly / Anna Friel / Alice Cooper
Episode 23 · 60 min
Jennifer Love Hewitt / Jim Parsons
Episode 24 · 60 min
Lauren Graham / Patrick Pedraja / Michael Franti & Spearhead
Episode 25 · 60 min
Margaret Cho / Randy Newman / Randy Newman
Episode 26 · 60 min
Seth Green / Betty White / Smothers Brothers
Episode 27 · 60 min
Thandie Newton / Barry Sonnenfeld / Jim Bianco
Episode 28 · 60 min
Rufus Sewell / Natasha Bedingfield
Episode 29 · 60 min
Russell Crowe / Jennifer Esposito
Episode 30 · 60 min
Matt Lucas & David Walliams / Tom Morello
Episode 31 · 60 min
Dee Dee Myers / Noah Emmerich
Episode 32 · 60 min
Rachael Ray / Leanne Marshall / Laura Marling
Episode 33 · 60 min
Chris Matthews / Christopher Mintz-Plasse
Episode 34 · 60 min
John Malkovich / Little Jackie
Episode 35 · 60 min
Mo'Nique / Bill Santiago / Lenka
Episode 36 · 60 min
Kathy Griffin / Carl Bernstein
Episode 37 · 60 min
Pepe the King Prawn / Saffron Burrows
Episode 38 · 60 min
Ben Stein / Parminder Nagra / The New York Dolls
Episode 39 · 60 min
Kevin Smith / Kaitlin Olson
Episode 40 · 60 min
Lauren Graham / The Damned
Episode 41 · 60 min
Bill Maher
Episode 42 · 60 min
Paris Hilton / Drew Pinsky
Episode 43 · 60 min
Elizabeth Banks / Jay Mohr
Episode 44 · 60 min
Christian Slater / Luke Dempsey / Eric Hutchinson
Episode 45 · 60 min
Mark Harmon / Ron White
Episode 46 · 60 min
Coolio / Tom Dreesen / Tim Reid
Episode 47 · 60 min
Seann William Scott / Kathy Kinney
Episode 48 · 60 min
Andy Richter / Cold War Kids
Episode 49 · 60 min
Jim Parsons / Ray Davies
Episode 50 · 60 min
Poppy Montgomery / Nick Hornby
Episode 51 · 60 min
Steve Harvey / Sarah Shahi / The Bacon Brothers
Episode 52 · 60 min
James Lipton / Sara Gilbert / Sarah McLachlan
Episode 53 · 60 min
Larry the Cable Guy / Third Day
Episode 54 · 60 min
George Hamilton / Cobie Smulders
Episode 55 · 60 min
Eamonn Walker / Low vs Diamond
Episode 56 · 60 min
Neil Patrick Harris / Julia Fordham
Episode 57 · 60 min
Adam Arkin / Jen Kirkman / Adele
Episode 58 · 60 min
Tony Curtis / Megalyn Echikunwoke / Oppenheimer
Episode 59 · 60 min
Kristin Chenoweth / Diedrich Bader
Episode 60 · 60 min
Chi McBride / Seal
Episode 61 · 60 min
Elizabeth Banks / Ken Tucker
Episode 62 · 60 min
Alfred Molina / Tokyo Police Club
Episode 63 · 60 min
Brooke Shields / Dom Irrera
Episode 64 · 60 min
Carrie Fisher / Julie Benz
Episode 65 · 60 min
Carmen Electra / Dennis Lehane
Episode 66 · 60 min
Don Rickles / Joanna Garcia
Episode 67 · 60 min
Samuel L. Jackson / Death Cab for Cutie
Episode 68 · 60 min
Julia Ormond / Michael Connelly
Episode 69 · 60 min
Jeffrey Tambor / Patrick Keane
Episode 70 · 60 min
Joel McHale / Matt Nathanson
Episode 71 · 60 min
Billy Bob Thornton / Conor Oberst
Episode 72 · 60 min
Kristen Bell / Wolfgang Puck
Episode 73 · 60 min
Richard Lewis / Tracie Thoms
Episode 74 · 60 min
Marisa Tomei / Pauley Perrette
Episode 75 · 60 min
William Shatner / Jazmine Sullivan
Episode 76 · 60 min
Amy Sedaris / Dennis Haysbert
Episode 77 · 60 min
Ted Danson / Paula Poundstone
Episode 78 · 60 min
John Corbett / Tracie Thoms
Episode 79 · 60 min
Kristin Scott Thomas / Josh Jackson
Episode 80 · 60 min
John Waters / Norah O'Donnell
Episode 81 · 60 min
Wanda Sykes / Glasvegas
Episode 82 · 60 min
Dev Patel / Greg Proops
Episode 83 · 60 min
Sarah Chalke / Jeffrey Dean Morgan / Seal
Episode 84 · 60 min
Joel McHale / The Submarines
Episode 85 · 60 min
Trace Adkins / Perez Hilton
Episode 86 · 60 min
Jennifer Love Hewitt / Matthew Rhys
Episode 87 · 60 min
James Earl Jones / Rosemarie DeWitt
Episode 88 · 60 min
Chris Matthews / Paul Morrissey
Episode 89 · 60 min
RZA / Jared Harris
Episode 90 · 60 min
Cuba Gooding Jr. / Freida Pinto
Episode 91 · 60 min
Dominic Monaghan / Rosemarie DeWitt
Episode 92 · 60 min
Michael Sheen / Russell Peters / Sharon Jones & The Dap-Kings
Episode 93 · 60 min
Alfred Molina / Lance Burton
Episode 94 · 60 min
Robin Williams / Jason Randal
Episode 95 · 60 min
Samuel L. Jackson / Jason Hudy
Episode 96 · 60 min
Garry Shandling / Ed Alonzo
Episode 97 · 60 min
Kristen Bell / Franz Ferdinand
Episode 98 · 60 min
Michael Clarke Duncan / Richard Zoglin / Adele
Episode 99 · 60 min
Sean Combs / Olivia Williams
Episode 100 · 60 min
Steve Coogan / Connie Britton
Episode 101 · 60 min
Lewis Black / Shirley Manson
Episode 102 · 60 min
Tom Selleck / Glen Campbell
Episode 103 · 60 min
David Boreanaz / Philip Johnson / Zac Brown Band
Episode 104 · 60 min
Bill Maher / Chris Klein
Episode 105 · 60 min
Wynonna / Peter Bart
Episode 106 · 60 min
Paula Abdul / Carl Edwards
Episode 107 · 60 min
Rosie O'Donnell / The Knux
Episode 108 · 60 min
Paris Hilton / Dee Dee Myers
Episode 109 · 60 min
Kristin Davis / Wolfgang Puck
Episode 110 · 60 min
Desmond Tutu
Episode 111 · 60 min
Holly Hunter / Andrew Bird
Episode 112 · 60 min
Amy Adams / M Ward / Nick Griffin
Episode 113 · 60 min
Jason Segel / Dave Attell
Episode 114 · 60 min
Rosario / Gordon Ramsay
Episode 115 · 60 min
Tim Daly / Kara Cooney
Episode 116 · 60 min
Jim Parsons / Sara Bareilles
Episode 117 · 60 min
Christina Ricci / Mike Birbiglia
Episode 118 · 60 min
Regis Philbin / The Upper Crust
Episode 119 · 60 min
Julia Louis-Dreyfus / Dropkick Murphys
Episode 120 · 60 min
Steven Wright / Rashida Jones
Episode 121 · 60 min
Paul Rudd / George Wallace
Episode 122 · 60 min
Virginia Madsen / Jason Ritter / Chicago
Episode 123 · 60 min
Jerry O'Connell / Tucker Albrizzi / Patrick Pedraja / Ra Ra Riot
Episode 124 · 60 min
William Shatner / Regina King
Episode 125 · 60 min
Isabella Rossellini / Linda Cardellini
Episode 126 · 60 min
Jennifer Tilly / Heidi Newfield
Episode 127 · 60 min
Brittany Murphy / Christopher Gorham
Episode 128 · 60 min
Zooey Deschanel / Lance Krall
Episode 129 · 60 min
Dwight Yoakam / Mary McCormack
Episode 130 · 60 min
Adam Goldberg / Anna Gunn / Brett Dennen
Episode 131 · 60 min
Michael Caine / Matt Beatz
Episode 132 · 60 min
Madeleine Albright / Amy Smart
Episode 133 · 60 min
Jessica Lange / Tom Lennon / Madeleine Peyroux
Episode 134 · 60 min
Simon Cowell / Jean Smart / Erin McCarley
Episode 135 · 60 min
Rob Morrow / Jean-Michel Cousteau
Episode 136 · 60 min
Bob Barker / Jean Smart
Episode 137 · 60 min
Teri Hatcher / Martina McBride
Episode 138 · 60 min
Eddie Izzard / Chris Botti
Episode 139 · 60 min
Shirley Manson / Breckin Meyer
Episode 140 · 60 min
John McEnroe / Stana Katic
Episode 141 · 60 min
Kenneth Branagh / Antony and the Johnsons
Episode 142 · 60 min
Michael Douglas / Carrie Ann Inaba
Episode 143 · 60 min
Henry Winkler / Ricky Hatton
Episode 144 · 60 min
Jeffrey Dean Morgan / Stana Katic
Episode 145 · 60 min
George Hamilton / Jenny Lewis
Episode 146 · 60 min
Melina Kanakaredes / Nathan Fillion / Zac Brown Band
Episode 147 · 60 min
Matthew McConaughey / Cokie Roberts
Episode 148 · 60 min
Amy Smart / Kunal Nayyar
Episode 149 · 60 min
Steven Wright / Bryce Dallas Howard
Episode 150 · 60 min
Paulina Porizkova / Andy Nulman
Episode 151 · 60 min
Laurence Fishburne / Paula Poundstone
Episode 152 · 60 min
Howie Mandel / Laura Lippman
Episode 153 · 60 min
Ewan McGregor / All American Rejects
Episode 154 · 60 min
Justin Long / Lawrence Block
Episode 155 · 60 min
Kathy Griffin / Nelson George
Episode 156 · 60 min
Guy Pearce / Hattie Hayridge
Episode 157 · 60 min
John Waters / Manda Mosher
Episode 158 · 60 min
Mark Ruffalo / Mindy Kaling / The Decemberists
Episode 159 · 60 min
Bob Saget / P. W. Singer
Episode 160 · 60 min
Chris Isaac / Moon Bloodgood
Episode 161 · 60 min
Mary-Louise Parker / Guillermo del Toro / Tori Amos
Episode 162 · 60 min
Denis Leary / Diane Birch
Episode 163 · 60 min
Jeffrey Tambor / Gabrielle Anwar
Episode 164 · 60 min
Elizabeth Perkins / Mark Burnett / Bernie Williams
Episode 165 · 60 min
Chris Kattan / Henry Cho
Episode 166 · 60 min
Kevin Bacon / Michael Irvin
Episode 167 · 60 min
Dame Edna Everage
Episode 168 · 60 min
Chris Matthews / Theresa Andersson
Episode 169 · 60 min
Larry King / Anna Friel
Episode 170 · 60 min
Dane Cook / Peter Travers
Episode 171 · 60 min
Holly Hunter / Camera Obscura
Episode 172 · 60 min
Jeff Foxworthy / Gavin DeGraw
Episode 173 · 60 min
Julia Ormond / Derrick Pitts
Episode 174 · 60 min
Sandra Bullock / Metric / David Feldman
Episode 175 · 60 min
Bryan Cranston / Ben Kweller
Episode 176 · 60 min
Marion Cotillard / Michael Musto
Episode 177 · 60 min
Jim Parsons / James Frey
Episode 178 · 60 min
Mary Steenburgen / Bettye LaVette / Todd Sawyer
Episode 179 · 60 min
Larry David / Wolfgang Puck
Episode 180 · 60 min
Lisa Kudrow
Episode 181 · 60 min
Eric Idle / Dr. Lisa Masterson
Episode 182 · 60 min
Evan Rachel Wood / Christopher Gorham
Episode 183 · 60 min
Julie Chen / Michael Ian Black / Will Dailey
Episode 184 · 60 min
Jeff Goldblum / Jackie Collins
Episode 185 · 60 min
Ray Romano / Michael Bublé
Episode 186 · 60 min
Selma Blair / Connie Schultz
Episode 187 · 60 min
John Larroquette / Will Dailey / Charlie Viracola
Episode 188 · 60 min
Rosie Perez / Mike Massimino
Episode 189 · 60 min
Isaac Mizrahi / Shohreh Aghdashloo
Episode 190 · 60 min
Paris Hilton / Alan Furst / Ray LaMontagne
Episode 191 · 60 min
Margaret Cho / Michael Lewis / Eric Church
Episode 192 · 60 min
Gerard Butler / Jackie Collins
Episode 193 · 60 min
Tom Lennon / Kelly Rowland / Dobie Maxwell
Episode 194 · 60 min
Cheryl Hines / Ben Mezrich
Episode 195 · 60 min
Rashida Jones / José Andrés / Jim Breuer
Episode 196 · 60 min
Chelsea Handler / Richard Wolffe
Episode 197 · 60 min
Christiane Amanpour / Johnny Galecki
Episode 198 · 60 min
Toni Collette / Rodney Carrington
Episode 199 · 60 min
James Spader / Rose Byrne
Episode 200 · 60 min
Saffron Burrows
Episode 201 · 60 min
Edie Falco / Les Stroud / Lisa Landry
Episode 202 · 60 min
Tony Shalhoub / Minka Kelly
Episode 203 · 60 min
Wolf Blitzer / Rose Byrne
Episode 204 · 60 min
Zooey Deschanel / Glasvegas
Episode 205 · 60 min
Don Rickles / Sharon Jones & The Dap-Kings
Episode 206 · 60 min
Carrot Top / Alexis Bledel
Episode 207 · 60 min
Betty White / Mitch Albom / Bonnie Raitt & Taj Mahal
Episode 208 · 60 min
Eric Bana / Holly Williams
Episode 209 · 60 min
Jon Cryer
Episode 210 · 60 min
Liza Minnelli / Kara Cooney
