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Biologist Hu Shuo, in a desperate attempt to save his son suffering from a genetic defect, conducts research on using ant DNA to enhance human genes. However, his controversial work is met with widespread rejection, and even his wife, Liu Xingzhi, leaves him. When Huang Jinxiong, a wealthy benefactor battling illness, funds Hu Shuo's research, a catastrophic accident occurs during his lab visit—the escaped queen ant mutates and leads a swarm of ants in a vicious attack. As the chaos unfolds, both Hu Shuo and Huang Jinxiong begin undergoing horrifying ant-like mutations...